The medical Dr. Owen leads a three-men SWAT team inside the sealed off building to get blood sample from the girl Medeiros to develop an antidote. They are attacked by the zombie-like creatures and Dr. Owen locks a zombie inside a room using a crucifix. He discloses that the patient zero was possessed by the evil and the Vatican sent him to save mankind. Further, they will only leave the building under his voice command. Meanwhile, three teenagers follow a fireman and a man that breaks into the building through the sewage system to rescue his colleague and daughter respectively and they are trapped inside. They are lured and release the evil creature that was locked by Dr. Owen in a room. Out of the blue, the lead team meets the journalist Ângela Vidal hidden inside the building.

A young journalist long ago rejected by his now aged and dying father finds himself investigating one of his father's former friends, a candidate for canonization. Uncovering the two men's complicated relationship from childhood through the horrors of the Spanish Civil War unveils a compelling drama filled with passion, betrayal, love and religion. An action packed story set during a murderous time in history that ultimately serves the present by revealing the importance and timeless power of forgiveness.